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Index > Protein center > LTF(Gene name) > Bovine
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  • LTF (Gene name),
  • Lactotransferrin (Protein name ),  TRFL_BOVIN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Related Databases
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  • Gene name:
    LTF;
    Protein name:
    Lactotransferrin(Lactoferrin);
    Alternative:

    Organism:
    Bovine (Bos taurus). 
    General Annotation
    Sub Unit:
    Monomer.
    Function:
    The lactotransferrin transferrin-like domain 1 functions as a serine protease of the peptidase S60 family that cuts arginine rich regions. This function contributes to the antimicrobial activity.
    Subcellular Location:
    Secreted
    Protein Attributes:
    Sequence length:
    708
    Sequence:
    50:
    MKLFVPALLS | LGALGLCLAA | PRKNVRWCTI | SQPEWFKCRR | WQWRMKKLGA | 
    100:
    PSITCVRRAF | ALECIRAIAE | KKADAVTLDG | GMVFEAGRDP | YKLRPVAAEI | 
    150:
    YGTKESPQTH | YYAVAVVKKG | SNFQLDQLQG | RKSCHTGLGR | SAGWIIPMGI | 
    200:
    LRPYLSWTES | LEPLQGAVAK | FFSASCVPCI | DRQAYPNLCQ | LCKGEGENQC | 
    250:
    ACSSREPYFG | YSGAFKCLQD | GAGDVAFVKE | TTVFENLPEK | ADRDQYELLC | 
    300:
    LNNSRAPVDA | FKECHLAQVP | SHAVVARSVD | GKEDLIWKLL | SKAQEKFGKN | 
    350:
    KSRSFQLFGS | PPGQRDLLFK | DSALGFLRIP | SKVDSALYLG | SRYLTTLKNL | 
    400:
    RETAEEVKAR | YTRVVWCAVG | PEEQKKCQQW | SQQSGQNVTC | ATASTTDDCI | 
    450:
    VLVLKGEADA | LNLDGGYIYT | AGKCGLVPVL | AENRKSSKHS | SLDCVLRPTE | 
    500:
    GYLAVAVVKK | ANEGLTWNSL | KDKKSCHTAV | DRTAGWNIPM | GLIVNQTGSC | 
    550:
    AFDEFFSQSC | APGADPKSRL | CALCAGDDQG | LDKCVPNSKE | KYYGYTGAFR | 
    600:
    CLAEDVGDVA | FVKNDTVWEN | TNGESTADWA | KNLNREDFRL | LCLDGTRKPV | 
    650:
    TEAQSCHLAV | APNHAVVSRS | DRAAHVKQVL | LHQQALFGKN | GKNCPDKFCL | 
    700:
    FKSETKNLLF | NDNTECLAKL | GGRPTYEEYL | GTEYVTAIAN | LKKCSTSPLL | 
    708:
    EACAFLTR
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    Pfam:
    String:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Bovine Lactoferrin
    Cat.:
    E0780h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Bovine Lactoferrin
    Cat.:
    E0780m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Bovine Lactoferrin
    Cat.:
    E0780b
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    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Bovine Lactoferrin
    Cat.:
    E0780p
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    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Bovine Lactoferrin
    Cat.:
    U0780h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Bovine Lactoferrin
    Cat.:
    U0780b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Bovine Lactoferrin
    Cat.:
    U0780p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Bovine Lactoferrin
    Cat.:
    U0780m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Bovine Lactoferrin
    Polyclonal Antibody for Bovine Lactoferrin
    Polyclonal Antibody for Bovine Lactoferrin
    Cat.:
    P0780Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Bovine Lactoferrin
    Cat.:
    P0780Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Bovine Lactoferrin
    Monoclonal Antibody for Bovine Lactoferrin
    Monoclonal Antibody for Bovine Lactoferrin
    Monoclonal Antibody for Bovine Lactoferrin
    Protein for Bovine Lactoferrin
    Protein for Bovine Lactoferrin
    Protein for Bovine Lactoferrin
    Protein for Bovine Lactoferrin

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Molecular cloning and sequence analysis of bovine lactotransferrin."
      Pierce A. , Colavizza D. , Benaissa M. , Maes P. , Tartar A. , Montreuil J. , Spik G.
      Eur. J. Biochem.196:177-184(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Submandibular gland.
    2. 2.
      "Bovine lactoferrin mRNA: sequence, analysis, and expression in the mammary gland."
      Goodman R.E. , Schanbacher F.L.
      Biochem. Biophys. Res. Commun.180:75-84(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    3. 3.
      "Cloning of a 80-kD advanced glycosylation end product (AGE) binding protein from bovine lung."
      Tsang T.C. , Burns D.K. , Wang F. , Pan Y.C.E. , Schmidt A.M. , Stern D.
      FASEB J.6:233-233(1991)
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Lung.
    4. 4.
      "Structure of the bovine lactoferrin-encoding gene and its promoter."
      Seyfert H.-M. , Tuckoricz A. , Interthal H. , Koczan D. , Hobom G.
      Gene143:265-269(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA]
      tissue: Blood.
      tissue: Mammary gland.
    5. 5.
      "Bovine lactoferrin."
      Nakamura I. , Shimazaki K. , Yagi Y. , Watanabe A.
      Submitted (2000-07) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    6. 6.
      NIH - Mammalian Gene Collection (MGC) project
      Submitted (2006-05) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: Hereford.
      tissue: Ascending colon.
    7. 7.
      "Purification and characterization of bovine lactoferrin from secretions of the involuting mammary gland: identification of multiple molecular weight forms."
      Rejman J.J. , Hegarty H.M. , Hurley W.L.
      Comp. Biochem. Physiol.93B:929-934(1989) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 20-59
    8. 8.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 36-60;IDENTIFICATION OF LACTOFERRICIN PEPTIDE;FUNCTION;SYNTHESIS OF 36-60
      tissue: Milk.
    9. 9.
      "Antibacterial activity in bovine lactoferrin-derived peptides."
      Hoek K.S. , Milne J.M. , Grieve P.A. , Dionysius D.A. , Smith R.
      Antimicrob. Agents Chemother.41:54-59(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION OF LACTOFERRICIN
    10. 10.
      "Antibacterial effect of bovine lactoferrin against udder pathogens."
      Kutila T. , Pyorala S. , Saloniemi H. , Kaartinen L.
      Acta Vet. Scand.44:35-42(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ANTIMICROBIAL ACTIVITY
    11. 11.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEASE FUNCTION;BIOPHYSICOCHEMICAL PROPERTIES
    12. 12.
      "Lactoferrin is a potent regulator of bone cell activity and increases bone formation in vivo."
      Cornish J. , Callon K.E. , Naot D. , Palmano K.P. , Banovic T. , Bava U. , Watson M. , Lin J.M. , Tong P.C. , Chen Q. , Chan V.A. , Reid H.E. , Fazzalari N. , Baker H.M. , Baker E.N. , Haggarty N.W. , Grey A.B. , Reid I.R.
      Endocrinology145:4366-4374(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
    13. 13.
      "Human lactoferrin activates NF-kappaB through the Toll-like receptor 4 pathway while it interferes with the lipopolysaccharide-stimulated TLR4 signaling."
      Ando K. , Hasegawa K. , Shindo K. , Furusawa T. , Fujino T. , Kikugawa K. , Nakano H. , Takeuchi O. , Akira S. , Akiyama T. , Gohda J. , Inoue J. , Hayakawa M.
      FEBS J.277:2051-2066(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
    14. 14.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ERRATUM
    15. 15.
      "Three-dimensional structure of diferric bovine lactoferrin at 2.8-A resolution."
      Moore S.A. , Anderson B.F. , Groom C.R. , Haridas M. , Baker E.N.
      J. Mol. Biol.274:222-236(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.8 ANGSTROMS)
    16. 16.
      "Three-dimensional solution structure of lactoferricin B, an antimicrobial peptide derived from bovine lactoferrin."
      Hwang P.M. , Zhou N. , Shan X. , Arrowsmith C.H. , Vogel H.J.
      Biochemistry37:4288-4298(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 36-60
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