Protein name:
Lactotransferrin (Lactoferrin) ;
Alternative:
Organism:
Bovine (Bos taurus).
General Annotation
Function:
The lactotransferrin transferrin-like domain 1 functions as a serine protease of the peptidase S60 family that cuts arginine rich regions. This function contributes to the antimicrobial activity.
Subcellular Location:
Secreted
Protein Attributes:
50:
MKLFVPALLS | LGALGLCLAA | PRKNVRWCTI | SQPEWFKCRR | WQWRMKKLGA |
100:
PSITCVRRAF | ALECIRAIAE | KKADAVTLDG | GMVFEAGRDP | YKLRPVAAEI |
150:
YGTKESPQTH | YYAVAVVKKG | SNFQLDQLQG | RKSCHTGLGR | SAGWIIPMGI |
200:
LRPYLSWTES | LEPLQGAVAK | FFSASCVPCI | DRQAYPNLCQ | LCKGEGENQC |
250:
ACSSREPYFG | YSGAFKCLQD | GAGDVAFVKE | TTVFENLPEK | ADRDQYELLC |
300:
LNNSRAPVDA | FKECHLAQVP | SHAVVARSVD | GKEDLIWKLL | SKAQEKFGKN |
350:
KSRSFQLFGS | PPGQRDLLFK | DSALGFLRIP | SKVDSALYLG | SRYLTTLKNL |
400:
RETAEEVKAR | YTRVVWCAVG | PEEQKKCQQW | SQQSGQNVTC | ATASTTDDCI |
450:
VLVLKGEADA | LNLDGGYIYT | AGKCGLVPVL | AENRKSSKHS | SLDCVLRPTE |
500:
GYLAVAVVKK | ANEGLTWNSL | KDKKSCHTAV | DRTAGWNIPM | GLIVNQTGSC |
550:
AFDEFFSQSC | APGADPKSRL | CALCAGDDQG | LDKCVPNSKE | KYYGYTGAFR |
600:
CLAEDVGDVA | FVKNDTVWEN | TNGESTADWA | KNLNREDFRL | LCLDGTRKPV |
650:
TEAQSCHLAV | APNHAVVSRS | DRAAHVKQVL | LHQQALFGKN | GKNCPDKFCL |
700:
FKSETKNLLF | NDNTECLAKL | GGRPTYEEYL | GTEYVTAIAN | LKKCSTSPLL |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
Bovine
Pig
ELISA Kit for Bovine Lactoferrin
ELISA Kit for Bovine Lactoferrin
ELISA Kit for Bovine Lactoferrin
ELISA Kit for Bovine Lactoferrin
CLIA Kit for Bovine Lactoferrin
CLIA Kit for Bovine Lactoferrin
CLIA Kit for Bovine Lactoferrin
CLIA Kit for Bovine Lactoferrin
Polyclonal Antibody for Bovine Lactoferrin
Polyclonal Antibody for Bovine Lactoferrin
Polyclonal Antibody for Bovine Lactoferrin
Polyclonal Antibody for Bovine Lactoferrin
Monoclonal Antibody for Bovine Lactoferrin
Monoclonal Antibody for Bovine Lactoferrin
Monoclonal Antibody for Bovine Lactoferrin
Monoclonal Antibody for Bovine Lactoferrin
Protein for Bovine Lactoferrin
Protein for Bovine Lactoferrin
Protein for Bovine Lactoferrin
Protein for Bovine Lactoferrin
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
tissue :
Submandibular gland .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
tissue :
Lung .
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA]
tissue :
Blood .
tissue :
Mammary gland .
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain :
Hereford .
tissue :
Ascending colon .
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PROTEIN SEQUENCE OF 20-59
8.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PROTEIN SEQUENCE OF 36-60;IDENTIFICATION OF LACTOFERRICIN PEPTIDE;FUNCTION;SYNTHESIS OF 36-60
tissue :
Milk .
9.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION OF LACTOFERRICIN
10.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : ANTIMICROBIAL ACTIVITY
11.
"Proteolytic activity of bovine lactoferrin."
Massucci M.T.
,
Giansanti F.
,
Di Nino G.
,
Turacchio M.
,
Giardi M.F.
,
Botti D.
,
Ippoliti R.
,
De Giulio B.
,
Siciliano R.A.
,
Donnarumma G.
,
Valenti P.
,
Bocedi A.
,
Polticelli F.
,
Ascenzi P.
,
Antonini G.
BioMetals17:249-255(2004)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PROTEASE FUNCTION;BIOPHYSICOCHEMICAL PROPERTIES
12.
"Lactoferrin is a potent regulator of bone cell activity and increases bone formation in vivo."
Cornish J.
,
Callon K.E.
,
Naot D.
,
Palmano K.P.
,
Banovic T.
,
Bava U.
,
Watson M.
,
Lin J.M.
,
Tong P.C.
,
Chen Q.
,
Chan V.A.
,
Reid H.E.
,
Fazzalari N.
,
Baker H.M.
,
Baker E.N.
,
Haggarty N.W.
,
Grey A.B.
,
Reid I.R.
Endocrinology145:4366-4374(2004)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION
13.
"Human lactoferrin activates NF-kappaB through the Toll-like receptor 4 pathway while it interferes with the lipopolysaccharide-stimulated TLR4 signaling."
Ando K.
,
Hasegawa K.
,
Shindo K.
,
Furusawa T.
,
Fujino T.
,
Kikugawa K.
,
Nakano H.
,
Takeuchi O.
,
Akira S.
,
Akiyama T.
,
Gohda J.
,
Inoue J.
,
Hayakawa M.
FEBS J.277:2051-2066(2010)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION
14.
Massucci M.T.
,
Giansanti F.
,
Di Nino G.
,
Turacchio M.
,
Giardi M.F.
,
Botti D.
,
Ippoliti R.
,
De Giulio B.
,
Siciliano R.A.
,
Donnarumma G.
,
Valenti P.
,
Bocedi A.
,
Polticelli F.
,
Ascenzi P.
,
Antonini G.
BioMetals17:745-745(2004)
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : ERRATUM
15.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : X-RAY CRYSTALLOGRAPHY (2.8 ANGSTROMS)
16.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : STRUCTURE BY NMR OF 36-60